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These asthma medications dilate the bronchial tubes and make breathing easier by relaxing the smooth muscle that constrict the bronchi (airways), which is why they are known as bronchodilators.
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These drugs act slowly, over the course of days, to help prevent attacks and reduce shortness of breath.
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Canadian product information states that formoterol is used in children 6 years of age and older.
The long-acting beta2 agonist bronchodilators include formoterol (Foradil) and salmeterol (Serevent).
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If you are aged 40 to 74, have emphysema, do not have active asthma or chronic bronchitis, and if you would be willing to abstain from smoking for up to four months, you may qualify for this study.
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In November 2005, the US released a health advisory, alerting the public to findings that show the use of long-acting β 2 agonists could lead to a worsening of symptoms, and in some cases death.
These results led to stopping the study prematurely (see CLINICAL TRIALS: Asthma: Salmeterol Multi-center Asthma Research Trial).
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Osteoporosis, heart disease, muscle wasting and depression are all more common in people with COPD.
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Some short-acting β-agonists (for example ) are specific to the lungs; they are called β2-agonists and can relieve bronchospasms without unwanted cardiac (β1) side effects of nonspecific β-agonists (for example, ephedrine or epinephrine).
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The data for triple therapy are inconsistent, with studies showing improvement in lung function and symptom scores but conflicting results regarding reduction in exacerbation rates compared with tiotropium alone.
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In a large clinical study, more patients with asthma who used salmeterol experienced severe episodes of asthma that had to be treated in a hospital or caused death than patients with asthma who did not use salmeterol.
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Use a short-acting, inhaled β 2-agonist, not salmeterol (alone or in fixed combination with fluticasone), to relieve acute symptoms such as shortness of breath.
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