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You should not use this medication if you have untreated or uncontrolled high blood pressure, if you are allergic to epoetin alfa or darbepoetin alfa (Aranesp), or if you have ever had pure red cell aplasia (PRCA, a type of anemia) caused by using either of these two drugs.
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As with any printed reference, the use of particular drugs, regimes and drug dosages may become out-of-date over time, since new information may have been published and become generally accepted after the latest update to this printed information.
These may be signs that your body has stopped responding to this medication.
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The usual therapy for anemia is outlined below.
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Biomedical System Dynamics to Improve Anemia Control With Darbepoetin Alfa in Long-Term Hemodialysis Patients.
Review article: Patient-level outcomes: the missing link.
This increase in fatigue was not explained by hormone therapy and approached clinically meaningful values.
High-flux versus low-flux membranes for end-stage kidney disease.
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The kinetics of the serum M component in each patient were analyzed by comparing the findings obtained during erythropoietin therapy with those obtained during the six months before the start of treatment.
The CDC recommends HIV testing as a part of standard prenatal care for all pregnant women.
Your doctor may prescribe a special diet to help control your blood pressure and to help increase your iron levels so that darbepoetin alfa injection can work as well as possible.
What are the common side effects of treatment with epoetin alfa?
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Authorised by the European Medicines Agency on 28 August 2007, it stimulates erythropoiesis and is used to treat anemia, commonly associated with chronic renal failure and cancer chemotherapy.
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The cancer tends to be diagnosed when it is widespread, affecting the spleen, bone marrow, and liver as well as abdominal lymph nodes.
Push the plunger of the syringe down to inject the air from the syringe into the epoetin alfa vial.
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The risk is highest at higher doses, in patients who receive other cardio-toxic medications, radiation to the chest area, and in children.
The proxy problem: Child report versus parent report in health-related quality of life research.
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Patients with end-stage renal disease (ESRD) are those patients with CRF who require regular dialysis or kidney transplantation for survival.
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Positive criteria now require detection of at least three consecutive bands with twofold greater intensity than those in the acidic region, thereby reducing further the possibility of false-positive results.
Ritonavir is a potent inhibitor of cytochrome P-450 3A4 metabolism and is used to increase the bioavailability of other PIs including indinavir, lopinavir, saquinavir, amprenavir, and atazanavir, thereby allowing for lower doses of these drugs.
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Current implementation of the FACIT questionnaires range in use from Phase I, II, and III clinical trials and other treatment evaluations, as an intervention tool in the clinical management of symptoms (both physical and psychological), and as an outcomes measure in health practice studies.
Left ventricular hypertrophy is a common disorder found in approximately 75% of patients who have not yet undergone dialysis.
ESA APPRISE Oncology Program has been set up to decrease the risks of using epoetin alfa injection to treat anemia caused by chemotherapy.
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High-Dose Recombinant Human Erythropoietin Stimulates Reticulocyte Production in Patients with Multiple Organ Dysfunction Syndrome.
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The maintenance dose must be individualized for each patient on dialysis.
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Use of erythropoiesis stimulating agents and intravenous iron for cancer and treatment-related anaemia: the need for predictors and indicators of effectiveness has not abated.
The Scope of Coronary Heart Disease in Patients With Chronic Kidney Disease.
Correction of Anemia with Erythropoietin in Chronic Kidney Disease (stage 3 or 4): Effects on Cardiac Performance.
This will produce results and will keep your RBC count increased for as much as three months, possibly longer.
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When initiating or adjusting therapy, monitor hemoglobin levels at least weekly until stable, then monitor at least monthly.
Red blood cell (RBC) transfusion rates among US chronic dialysis patients during changes to Medicare end-stage renal disease (ESRD) reimbursement systems and erythropoiesis stimulating agent (ESA) labels.
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Randomized clinical trials and systematic reviews of available randomized clinical trials demonstrate an increased risk of thromboembolism in patients receiving epoetin or darbepoetin.
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Impacts of Recombinant Human Erythropoietin Treatment During Predialysis Periods on the Progression of Chronic Kidney Disease in a Large-Scale Cohort Study (Co-JET study).
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Patients were followed for 6 weeks, with the exception of those in the IV bolus arm, who were followed until the end of their treatment course.
FDA Drug Safety Communication: Modified dosing recommendations to improve the safe use of Erythropoiesis-Stimulating Agents (ESAs) in chronic kidney disease.
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